Rob Partridge is expected to be sidelined for a minimum of three weeks with a broken collarbone he sustained during the Ronde van Overijssel on Saturday.
The 31-year-old crashed in the opening skirmishes of the UCI 1.2 contest in Rijssen. Early indications were he had escaped serious injury but after returning to England and waking up sore the next morning, an X-ray confirmed a clean fracture.
Partridge has been ruled out of the Lincoln Grand Prix on Sunday, while a seventh participation in the Ras, which begins on May 21, has also been scuppered.
The Welshman was set to captain the BIKE Channel Canyon squad in Ireland, having finish fourth and sixth on general classification in 2015 and 2010 respectively.
He finished third on stages in 2015 and 2014, while also donning the mountains jersey. His absence will be a major blow to sports director Tim Elverson, who will now look to shuffle his pack for the eight-day stage race.